Scott Gray, will make his first Scotland start since his debut cap, when he lines-up at openside flanker in Saturday’s Calcutta Cup clash at Twickenham. Gray, 31, replaces John Barclay in the only change to the starting XV for the final match in this season’s RBS 6 Nations Championship.There is one further change on the bench where Glasgow Warriors’ back-row forward Kelly Brown returns to the 22 having been 23rd man against Ireland.Scotland coach Frank Hadden said: “Scott has been knocking on the door for some time now and deserves this opportunity, while we’ve gone for Kelly on the bench for the coverage that he provides.”We’re looking forward to going to Twickenham and seeking back to back Calcutta Cup wins for the first time since 1984.”Scotland team (sponsor Murray) to play England in the RBS 6 Nations ChampionshipTwickenham on Saturday 21 March (kick-off 3.30pm)15 Chris Paterson (Edinburgh)14 Simon Danielli (Ulster)13 Max Evans (Glasgow Warriors)12 Graeme Morrison (Glasgow Warriors)11 Thom Evans (Glasgow Warriors)10 Phil Godman (Edinburgh)9 Mike Blair (Edinburgh) CAPTAIN1 Alasdair Dickinson (Gloucester)2 Ross Ford (Edinburgh)3 Euan Murray (Northampton Saints)4 Jason White (Sale Sharks)5 Jim Hamilton (Edinburgh)6 Alasdair Strokosch (Gloucester)8 Simon Taylor (Stade Francais)7 Scott Gray (Northampton Saints)Substitutes16 Dougie Hall (Glasgow Warriors)17 Moray Low (Glasgow Warriors)18 Nathan Hines (Perpignan)19 Kelly Brown (Glasgow Warriors)20 Chris Cusiter (Perpignan)21 Nick De Luca (Edinburgh)22 Hugo Southwell (Edinburgh)RefereeMarius Jonker (South Africa).  Touch-judges: Christophe Berdos (France) and Simon McDowell (Ireland).  TMO: Carlo Damasco (Italy)