In the front-row, Ben Mace packs down alongside Dan Gamble and Scott Clelland, while Alex Samuel links up with Struan Whitaker in the second-row.
Ben Muncaster anchors a back-row featuring Gregor Brown and openside flanker, Harri Morris.
Jamie Dobie gets the nod at scrum-half and Alex Harley completes the half-back pairing.
Scott King is deployed in midfield and is partnered by Matt Currie, while in the back-three Nathan Sweeney is joined by wingers Finlay Callaghan and Harry Patterson.
Following their opening match, the team will face Wales on Wednesday (17 April, kick-off 4.10pm) and Ireland on Sunday (21 April, kick-off 11.10am).
You can catch all the action on FreeSports and also follow live updates on @scotlandteam.
Scotland U18 team to face Italy U18 in the U18 Six Nations
15. Nathan Sweeney (Loretto School)*
14. Harry Patterson (Fettes College)
13. Matt Currie (Merchiston Castle School)*
12. Scott King (Heriot’s)*
11. Finlay Callaghan (GHK)
10. Alex Harley (George Watson’s College)
9. Jamie Dobie (Merchiston Castle School)*
1. Ben Mace (Stirling County)
2. Scott Clelland (Ayr)*
3. Dan Gamble (Merchiston Castle School)*
4. Alex Samuel (Madras / St Leonards)
5. Struan Whitaker (Edinburgh Accies)*
6. Gregor Brown (Robert Gordon’s College)
7. Harri Morris (George Watson’s College)
8. Ben Muncaster (Rugby School / Leicester Tigers)
Replacements
16. James Johnstone (Preston Lodge / Preston Lodge High School)*
17. Jamie Drummond (Marr)
18. Cole Lamberton (The Royal High School)
19. Jamie Campbell (Kelvinside Academy)
20. Rory Jackson (Kelvinside Academy)*
21. Cameron Scott (Preston Lodge)*
22. Joseph Strain (Dumfries Saints)
23. Cameron Furley (Saracens Academy / St Albans School)
24. Josh King (Queen Victoria School / Stirling County)*
25. Jordan Craig (Hamilton Bulls)
26. Tom Jones (Bristol Bears / SGS Filton)
*FOSROC Scottish Rugby Academy supported player